Intra-operative ketamine infiltration in tonsillar bed for relief of post-tonsillectomy pain
| Autor: | Sonbolestan SM, Barzegar F, Jamshidi M, Hashemi SM, Honarmand A |
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| Jazyk: | perština |
| Rok vydání: | 2008 |
| Předmět: | |
| Zdroj: | Tehran University Medical Journal, Vol 66, Iss 6, Pp 402-407 (2008) |
| Druh dokumentu: | article |
| ISSN: | 1683-1764 1735-7322 |
| Popis: | "nBackground: Post-tonsillectomy pain is often severe and usually prevents patients from routine eating and drinking. A new option for reducing postoperative pain is "preemptive analgesia", the pre-, intra- or post-operative administration of analgesic agents. Ketamine, an N-methyl D-aspartate receptor antagonist, has recently received attention for this aim. Herein, we study the effect of submucosal injection of ketamine in the tonsillar bed for the reduction of post-tonsillectomy pain. "nMethods: In this double-blind clinical trial, three groups of patients underwent infiltration of 0.5mg/kg ketamine, 1mg/kg ketamine or normal saline in their tonsillar bed. Age, sex and weight of patients, duration of surgery, systolic and diastolic blood pressure (before and after surgery), volume of blood loss, reoccurrence of bleeding, time to initiation of oral intake, nausea, vomiting, pain score and dysphasia were recorded in information sheet. Data analysis was performed by one-way ANOVA and chi squared tests, with significance at a P value of |
| Databáze: | Directory of Open Access Journals |
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