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Abstract Feverfew (Tanacetum parthenium) is one of the most important medicinal plants with different pharmacologic properties, such as anti-inflammatory, cardiotonic, antitumor and antiangiogenic activities. Parthenolide (PN) is a main bioactive molecule in feverfew which belongs to sesquiterpene lactone compounds. Currently, the plant cell suspension has been used as a useful method to produce secondary metabolites (SMs) components. Meanwhile, the elicitor application is an effective strategy to induce the production of SMs in plants. The present study was conducted as two different experiments in cell suspension of feverfew. In the first experiment, the effects of explant (shoot and root), hormone (TDZ + NAA and TDZ + 2. 4-D) on cell dry weight for one month were investigated. In the second experiment, the effect of elicitor (namely, MJ, YE and Ag+) and the hormones after 24, 48 and 72 h on PN content was assessed. The result of the first experiment revealed that the simple effects and the interaction of hormone × explant were significant (P |
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