Increased resistance rates of extended-spectrum β-lactamase-producing Enterobacterales isolated from blood cultures in Brazil

Autor: Raí Emanuel da Silva, Nathanael dos Santos Alves, Cynthia Karolina Rodrigues do Nascimento, Raylane Meneses Marques dos Santos, Wellerson Lucas de Pinho Barreto, Jadiel Silva Reis Filho, Victor Brito Dantas Martins, Erika Cecília Vallim Severino, Marcelo Costa Araújo, Miguel Araújo Rios Neto, Aline Dias Paiva, Kennio Ferreira-Paim, Fernanda Machado Fonseca
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Bioscience Journal, Vol 40, Pp e40040-e40040 (2024)
Druh dokumentu: article
ISSN: 1981-3163
DOI: 10.14393/BJ-v40n0a2024-69495
Popis: This study aimed to identify and evaluate the antimicrobial susceptibility profile of extended-spectrum β-lactamase (ESBL)-producing Enterobacterales isolated from blood cultures of patients with suspected sepsis. This retrospective cross-sectional epidemiological study was performed for four years (2015 to 2018) by accessing the medical records of patients diagnosed with bloodstream infections in two tertiary public hospitals in Brazil. Culture results and susceptibility tests of bacterial strains isolated from blood samples were analyzed. During four years, 2,263 blood culture exams were performed, and Enterobacterales were isolated in 694 (30.7%) samples. The disk approximation test detected ESBL production in 171 (24.6%) of the 694 isolated Enterobacterales (p
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