Differences between Belgian and Brazilian group A Streptococcus epidemiologic landscape.

Autor: Pierre Robert Smeesters, Anne Vergison, Dioclécio Campos, Eurico de Aguiar, Veronique Yvette Miendje Deyi, Laurence Van Melderen
Jazyk: angličtina
Rok vydání: 2006
Předmět:
Zdroj: PLoS ONE, Vol 1, p e10 (2006)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0000010
Popis: BACKGROUND: Group A Streptococcus (GAS) clinical and molecular epidemiology varies with location and time. These differences are not or are poorly understood. METHODS AND FINDINGS: We prospectively studied the epidemiology of GAS infections among children in outpatient hospital clinics in Brussels (Belgium) and Brasília (Brazil). Clinical questionnaires were filled out and microbiological sampling was performed. GAS isolates were emm-typed according to the Center for Disease Control protocol. emm pattern was predicted for each isolate. 334 GAS isolates were recovered from 706 children. Skin infections were frequent in Brasília (48% of the GAS infections), whereas pharyngitis were predominant (88%) in Brussels. The mean age of children with GAS pharyngitis in Brussels was lower than in Brasília (65/92 months, p
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