| Autor: |
Mina eRanjbaran, Athanasios eKatsarkas, Henrietta L. Galiana |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Frontiers in Computational Neuroscience, Vol 10 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
1662-5188 |
| DOI: |
10.3389/fncom.2016.00026 |
| Popis: |
The vestibulo-ocular reflex (VOR) is essential in our daily life to stabilize retinal images during head movements. Balanced vestibular functionality secures optimal reflex performance which can be distorted in case of peripheral vestibular lesions. Luckily, vestibular compensation in different neuronal sites restores VOR function to some extent over time. Studying vestibular compensation gives insight into the possible mechanisms for plasticity in the brain.In this work, novel experimental analysis tools are employed to reevaluate the VOR characteristics following unilateral vestibular lesions and compensation. Our results suggest that following vestibular lesions, asymmetric performance of the VOR is not only limited to its gain. Vestibular compensation also causes asymmetric dynamics, i.e. different time constants for the VOR during leftward or rightward passive head rotation. Potential mechanisms for these experimental observations are provided using simulation studies. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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