Autor: |
Injae Chung, John J. Wright, Hannah R. Bridges, Bozhidar S. Ivanov, Olivier Biner, Caroline S. Pereira, Guilherme M. Arantes, Judy Hirst |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-022-30506-1 |
Popis: |
Using cryo-EM, Chung et al. investigate conformational states of mammalian respiratory complex I to reveal an ubiquinone-10 molecule occupying the full length of the Q-binding channel. Molecular dynamics simulations suggest how the charge states of key residues influence the substrate binding pose. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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