Glycemic control and antidiabetic drugs in type 2 diabetes mellitus patients with renal complications

Autor: Huri HZ, Lim LP, Lim SK
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Drug Design, Development and Therapy, Vol 2015, Iss default, Pp 4355-4371 (2015)
Druh dokumentu: article
ISSN: 1177-8881
Popis: Hasniza Zaman Huri,1,2 Lay Peng Lim,1 Soo Kun Lim3 1Department of Pharmacy, Faculty of Medicine, University of Malaya, 2Clinical Investigation Centre, University Malaya Medical Centre, 3Renal Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia Background: Good glycemic control can delay the progression of kidney diseases in type 2 diabetes mellitus (T2DM) patients with renal complications. To date, the association between antidiabetic agents and glycemic control in this specific patient population is not well established.Purpose: This study aimed to identify antidiabetic regimens as well as other factors that associated with glycemic control in T2DM patients with different stages of chronic kidney disease (CKD).Patients and methods: This retrospective, cross-sectional study involved 242 T2DM inpatients and outpatients with renal complications from January 2009 to March 2014 and was conducted in a tertiary teaching hospital in Malaysia. Glycated hemoglobin (A1C) was used as main parameter to assess patients’ glycemic status. Patients were classified to have good (A1C
Databáze: Directory of Open Access Journals