Recent Microfluidic Innovations for Sperm Sorting

Autor: Maedeh Khodamoradi, Saeed Rafizadeh Tafti, Seyed Ali Mousavi Shaegh, Behrouz Aflatoonian, Mostafa Azimzadeh, Patricia Khashayar
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Chemosensors, Vol 9, Iss 6, p 126 (2021)
Druh dokumentu: article
ISSN: 2227-9040
DOI: 10.3390/chemosensors9060126
Popis: Sperm selection is a clinical need for guided fertilization in men with low-quality semen. In this regard, microfluidics can provide an enabling platform for the precise manipulation and separation of high-quality sperm cells through applying various stimuli, including chemical agents, mechanical forces, and thermal gradients. In addition, microfluidic platforms can help to guide sperms and oocytes for controlled in vitro fertilization or sperm sorting using both passive and active methods. Herein, we present a detailed review of the use of various microfluidic methods for sorting and categorizing sperms for different applications. The advantages and disadvantages of each method are further discussed and future perspectives in the field are given.
Databáze: Directory of Open Access Journals