| Autor: |
Mónica Vázquez-Del Mercado, Felipe de J Perez-Vazquez, Eduardo Gomez-Bañuelos, Efrain Chavarria-Avila, Arcelia Llamas-García, Karla I Arrona-Rios, Gustavo Ignacio Diaz-Rubio, Sergio Durán-Barragán, Rosa E Navarro-Hernández, Bethel P Jordán-Estrada, Natalia Prado-Bachega, Miguel A A Gonzalez-Beltran, Carlos Ramos-Becerra, Fernando Grover-Paez, David Cardona-Müller, Ernesto G Cardona-Muñoz |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
PLoS ONE, Vol 13, Iss 12, p e0207520 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0207520 |
| Popis: |
It is well known that cardiovascular diseases (CVD) are a major contributor of death in systemic lupus erythematosus (SLE) as well in other rheumatic illness. In the last decades, there has been a growing development of different methodologies with the purpose of early detection of CVD.ObjectiveThe aim of this study is to correlate the usefulness of subclinical parameters of vascular aging and QRISK 3-2017 score for early detection of CVD in SLE.MethodsClinical assessment including systemic lupus erythematosus disease activity index (SLEDAI) and systemic lupus international collaborating clinics / american college of rheumatology damage index (SLICC/ACR DI), laboratory measurements, carotid ultrasound examination, carotid intima media thickness (cIMT) measurement, carotid distention and diameter analysis, arterial stiffness measurement measured by tonometry and QRISK 3-2017 were done. All results were analyzed by SPSS 24 software.ResultsWe observed correlation between QRISK3 and mean cIMT (rs = 0.534, P < 0.001), PWV (rs = 0.474, P < 0.001), cfPWV (rs = 0.569, P < 0.001) and distensibility (rs = -0.420, P = 0.006). Consistent with above, SLE patients in middle and high risk QRISK 3-2017 showed increased arterial stiffness versus low risk group.ConclusionsWe encourage to the rheumatology community to assess cardiovascular risk in SLE patients with QRISK 3-2017 risk calculator as an alternative method at the outpatient clinic along a complete cardiovascular evaluation when appropriate. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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