Timing of adjuvant chemotherapy initiation and mortality among colon cancer patients at a safety-net health system

Autor:	Yan Lu, Aaron W. Gehr, Rachel J. Meadows, Bassam Ghabach, Latha Neerukonda, Kalyani Narra, Rohit P. Ojha
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Adjuvant chemotherapy Timing colon cancer Quality of care Prognosis Mortality Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Druh dokumentu:	article
ISSN:	1471-2407
DOI:	10.1186/s12885-022-09688-w
Popis:	Abstract Background Prior studies reported survival benefits from early initiation of adjuvant chemotherapy for stage III colon cancer, but this evidence was derived from studies that may be sensitive to time-related biases. Therefore, we aimed to estimate the effect of initiating adjuvant chemotherapy ≤8 or ≤ 12 weeks on overall and disease-free survival among stage III colon cancer patients using a study design that helps address time-related biases. Methods We used institutional registry data from JPS Oncology and Infusion Center, a Comprehensive Community Cancer Program. Eligible patients were adults aged
Databáze:	Directory of Open Access Journals
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