Estradiol and genistein effects on the sea bass (Dicentrarchus labrax) scales: Transcriptome dataset

Autor: Patricia I.S. Pinto, André R. Andrade, Michael A.S. Thorne, M. Dulce Estêvão, Adelino V.M. Canario, Deborah M. Power
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Data in Brief, Vol 27, Iss , Pp - (2019)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2019.104587
Popis: Fish scales are mineralized structures that play important roles in protection and mineral homeostasis. This tissue expresses multiple estrogen receptor subtypes and can be targeted by estrogens or estrogenic endocrine-disrupting compounds, but their effects are poorly explored. The transcriptome data here presented support the findings reported in the research article “Genistein and estradiol have common and specific impacts on the sea bass (Dicentrarchus labrax) skin-scale barrier” [1]. Juvenile sea bass were exposed to estradiol and the phytoestrogen genistein for 1 and 5 days, by intraperitoneal injections, and the effects on scale transcript expression were analysed by RNA-seq using an Illumina Hi-seq 1500. The raw reads of the 30 libraries produced have been deposited in the NCBI-SRA database with the project accession number SRP102504. Mapping of RNA-seq reads against the sea bass reference genome using the Cufflinks/TopHat package identified 371 genes that had significant (FDR
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