Pseudo-thrombocytopenia (PTCP). A challenge in the daily laboratory routine?

Autor: Schuff-Werner Peter, Mansour Joe, Gropp Angela
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Laboratory Medicine, Vol 44, Iss 5, Pp 295-304 (2020)
Druh dokumentu: article
ISSN: 2567-9430
2567-9449
2020-0099
DOI: 10.1515/labmed-2020-0099
Popis: Anticoagulation with ethylenediaminetetraacetic acid (EDTA) is a necessary pre-requisite for automated blood cell counting. With a prevalence of 0.01–1%, EDTA anticoagulation is accompanied by time- and temperature-dependent in vitro aggregation of platelets, resulting in false low counts. To avoid wrong clinical conclusions, spontaneous anticoagulant-induced platelet agglutination should therefore be recognized during analysis. This might be a challenge for the routine laboratory.
Databáze: Directory of Open Access Journals