| Autor: |
Su Jin You, Danbee Kang, Ji-Hee Sung, Hyejeong Park, Juhee Cho, Suk-Joo Choi, Soo-Young Oh, Cheong-Rae Roh |
| Jazyk: |
English<br />Korean |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Obstetrics & Gynecology Science, Vol 67, Iss 4, Pp 380-392 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2287-8580 |
| DOI: |
10.5468/ogs.24005 |
| Popis: |
Objective To assess the influence of advanced maternal age on congenital malformations, short- and long-term outcomes in offspring of nulligravida. Methods A retrospective study was conducted using the Korean National Health Insurance Service database spanning from January 2005 to December 2019. All live-born offspring of nulligravida (n=3,685,817) were included. The maternal age was subdivided into the following subgroups: 44 years (n=9,296). Outcomes were assessed based on International Classification of Diseases-10 codes. Adjusted odds ratios (aOR) were calculated with the group of 25-29 years as a reference. Result Most congenital malformations showed an age dependent increase, but cleft lip and abdominal wall defect exhibited a U-shape curve, indicating an increase even in those 44 years old and 1.18 (95% CI, 1.11-1.25) and 1.19 (95% CI, 1.09-1.30) in |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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