Efficacy and safety of ultrasound-guided thermal ablation of graves’ disease: a retrospective cohort study

Autor:	Guangzhen Cai, Beilin Luo, Maolin Wang, Jiqin Su, Luping Lin, Guibin Li, Xiangru Chen, Zhishu Huang, Peiyi Lin, Shengwei Liu, Huidi Yan, Lixin Zhou
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Thyroid Graves' disease Thermal ablation Retrospective study Efficacy assessment Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Thyroid Research, Vol 17, Iss 1, Pp 1-9 (2024)
Druh dokumentu:	article
ISSN:	1756-6614
DOI:	10.1186/s13044-024-00198-4
Popis:	Abstract Background Ultrasound-guided thermal ablation (TA) has emerged as a robust therapeutic approach for treating solid tumors in multiple organs, including the thyroid. Yet, its efficacy and safety profile in the management of Graves’ Disease (GD) remains to be definitively established. Methods A retrospective study was conducted on 50 GD patients treated with TA between October 2017 and December 2021. Key metrics like thyroid volume, volume reduction rate (VRR), thyroid hormones, and basal metabolic rate (BMR) were evaluated using paired Wilcoxon tests. Results The intervention of ultrasound-guided TA yielded a statistically significant diminution in total thyroid volume across all postoperative follow-up intervals—1, 3, 6, and 12 months—relative to pre-intervention baselines (p
Databáze:	Directory of Open Access Journals
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