New Gene Responsible for Resistance of Clinical Corynebacteria to Macrolide, Lincosamide and Streptogramin B

Autor: MAGDALENA SZEMRAJ, ANNA KWASZEWSKA, ELIGIA M. SZEWCZYK
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Polish Journal of Microbiology, Vol 67, Iss 2 (2018)
Druh dokumentu: article
ISSN: 1733-1331
2544-4646
DOI: 10.21307/pjm-2018-028
Popis: The subject of the study was phenotypic marking of the antibiotic susceptibility and MLSB resistance mechanism in Corynebacterium spp. isolated from human skin (18 isolates) and from clinical materials (19 isolates). The strains were tested for the presence of the erm(A), erm(B), erm(C), erm(X), lnu(A), msr(A), msr(B) and mph(C) genes. Clinical isolates showed wide resistance to antibiotics. In 89% clinical isolates and 72% skin microbiota a constitutive type of MLSB resistance was found. In 12 clinical isolates the erm(C) gene was detected-eight of which had erm(X) as well as erm(C), two harboured erm(X), erm(C) and erm(A) and two demonstrated only erm(C).
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