Investigation on nano microbial cellulose/honey composite for medical application

Autor: Amin Meftahi, Hamid Reza Shahriari, Ramin Khajavi, M Karim Rahimi, Ali Sharifian
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Materials Research Express, Vol 7, Iss 8, p 085003 (2020)
Druh dokumentu: article
ISSN: 2053-1591
DOI: 10.1088/2053-1591/aba8de
Popis: The overall purpose of this study is to investigate the plausibility of employing honey impregnated nano microbial cellulose (NMC) produced in Hestrin-Schramm media as a novel wound dressing. In the initial stage, three predominant characteristics of thyme, Astragalus, and Ziziphus honey including pH, total soluble solids as well as hydrogen peroxide content were assessed. In the second stage, the zone of inhibition diameters for Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. S.areous ) were examined respectively. Meanwhile, ATR-FTIR, XRD, and SEM were applied to study the chemical, physical structures, and surface morphology of NMC pellicle. In addition, Air permeability and wettability of samples were studied. The obtained results revealed that in spite of possessing the lowest amount of hydrogen peroxide, thyme honey had the uppermost antibacterial property. Furthermore, wettability and sinking time of treated NMC with thyme honey were 43% and 49% higher than the untreated NMC respectively and purified dry raw cellulose had 11% higher air permeability than dry raw cellulose in 400 Pa. According to the results, the treated NMC with thyme honey has a high potential to be applied in the medical field as a novel wound dressing.
Databáze: Directory of Open Access Journals