An Efficient Method to Calculate Genomic Prediction Accuracy for New Individuals

Autor: Mohammad H. Ferdosi, Natalie K. Connors, Bruce Tier
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Frontiers in Genetics, Vol 10 (2019)
Druh dokumentu: article
ISSN: 1664-8021
DOI: 10.3389/fgene.2019.00596
Popis: Diagonal elements of the coefficient matrix are necessary to calculate the genomic prediction accuracy. Here an improved methodology is described, to update the inverse of the coefficient matrix (C) for new individuals with a genotype, with and without phenotypes. Computational performance is significantly improved by re-using parts of the coefficient matrix inverse calculations that do not change from one animal to another, in combination with updated calculations for those that do change. This method expedites calculation of accuracy for new individuals with genotypes, without re-doing the whole population, by using the previously calculated matrices.
Databáze: Directory of Open Access Journals