Percutaneous Two-Dimensional Shear Wave Elastography for Diagnosis of Pancreatic Tumor

Autor: Yotaro Iino, Hitoshi Maruyama, Rintaro Mikata, Shin Yasui, Keisuke Koroki, Hiroki Nagashima, Masami Awatsu, Ayako Shingyoji, Yuko Kusakabe, Kazufumi Kobayashi, Soichiro Kiyono, Masato Nakamura, Hiroshi Ohyama, Harutoshi Sugiyama, Yuji Sakai, Tetsuhiro Chiba, Jun Kato, Toshio Tsuyuguchi, Naoya Kato
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Diagnostics, Vol 11, Iss 3, p 498 (2021)
Druh dokumentu: article
ISSN: 2075-4418
DOI: 10.3390/diagnostics11030498
Popis: Background: To investigate the efficacy of two-dimensional shear wave elastography (2D-SWE) for the diagnosis of pancreatic mass lesions. Methods: This ethics committee–approved cross-sectional study included 52 patients with histologically-proven pancreatic tumors (pancreatic ductal adenocarcinoma (PDAC), 36; tumor-forming pancreatitis (TFP), 15; neuroendocrine tumor, 1) and 33 control subjects. The 2D-SWE was performed for the tumor/non-tumor tissues, and SWE-mapping patterns and propagation quality were assessed. Results: Three mapping patterns were detected based on the size and distribution of the coloring areas. Pattern A (whole coloring) was detected in all non-tumor tissues and TFP, whereas pattern C (multiple small coloring spots) was detected in PDAC only. Pattern B (partial coloring with smaller spots) was detected in other lesions. The specificity and positive predictive value of pattern A for non-PDAC and those of pattern C for PDAC were 100%. The SWE value was higher in tumor lesions than in the non-tumor tissues (38.1 vs. 9.8 kPa; p < 0.001) in patients with PDAC. The SWE value in the non-tumor lesion was higher in patients with PDAC than in control (9.8 vs. 7.5 kPa; p < 0.001). Conclusions: 2D-SWE may play a role as a novel diagnostic tool for PDAC to detect a specific mapping pattern with quantitative assessment.
Databáze: Directory of Open Access Journals
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