HYPOFRACTIONATED RADIOTHERAPY WITH CONCURRENT CHEMOTHERAPY WITH WEEKLY CISPLATIN IN LOCALLY ADVANCED RELATIVELY RADIORESISTENT SUBSITES OF HEAD AND NECK CANCERS
| Autor: | K. Baidya, Y. S. Devi, A. S. Devi, Y. I. Singh, D. Das, R. Mahawar, N. N. Devi |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | International Journal of Medicine and Medical Research, Vol 8, Iss 2, Pp 24-33 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2413-6077 2414-9985 |
| DOI: | 10.11603/ijmmr.2413-6077.2022.2.13118 |
| Popis: | Background. Locoregionally advanced head and neck cancers are more aggressive and locoregional failure rate after conventional radiotherapy is high. Objective. The aim of the study is to assess the tumor response and toxicities of hypofractionated radiation therapy with concurrent chemotherapy in treatment of four relatively radioresistent tumor sites of head and neck. Methods. A prospective randomised control trial was conducted in 27 head and neck cancer patients. All patients were treated with hypofractionated radiotherapy at 250cGy/fraction once daily to a maximum of 62.5Gy in 25 fractions with concurrent cisplatin 30 mg/m2. Data were evaluated with SPSS version 21.0 for Windows with p-value |
| Databáze: | Directory of Open Access Journals |
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