Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2

Autor: Sounik Manna, Piyush Baindara, Santi M. Mandal
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Infection and Public Health, Vol 13, Iss 10, Pp 1397-1404 (2020)
Druh dokumentu: article
ISSN: 1876-0341
DOI: 10.1016/j.jiph.2020.07.003
Popis: Secondary bacterial infections are commonly associated with prior or concomitant respiratory viral infections. Viral infections damage respiratory airways and simultaneously defects both innate and acquired immune response that provides a favorable environment for bacterial growth, adherence, and facilitates invasion into healthy sites of the respiratory tract. Understanding the molecular mechanism of viral-induced secondary bacterial infections will provide us a chance to develop novel and effective therapeutic approaches for disease prevention. The present study describes details about the secondary bacterial infection during viral infections and their immunological changes.The outcome of discussion avails an opportunity to understand possible secondary bacterial infections associated with novel SARS-CoV-2, presently causing pandemic outbreak COVID-19.
Databáze: Directory of Open Access Journals