Intravenous Diclofenac Sodium Versus Ibuprofen as A Component of Multimodal Post Operative Analgesic Plan After Caesarean Section: A Double-Blinded Randomised Comparative Study
| Autor: | Mostafa Elawady, Basma Ghonim, Fatma Lahloub, Doaa Hellal, Hani Taman |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International Journal of Medical Arts, Vol 4, Iss 9, Pp 2619-2626 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2636-4174 2682-3780 |
| DOI: | 10.21608/ijma.2022.172220.1540 |
| Popis: | Background: Postoperative pain has a significant direct relationship to morbidity of female patients after caesarean section. Adequate post caesarean section pain management is fundamental. Objectives: To compare the postoperative analgesic effect of both ibuprofen and diclofenac sodium on pain score, rescue opioid requirement and patient satisfaction in female patients after caesarean section.Patients and methods: This prospective, randomised, double-blind comparative study was conducted over a period of eight months in Kafr Elsheikh University Hospital, obstetric unit. The study included any American Society of Anaesthesiologists [ASA] physical status II female patients aged 18–40 years who were scheduled for elective and emergency caesarean section under spinal anaesthesia. Patients were randomly allotted into two groups: Group D [intravenous diclofenac group] and Group I [intravenous ibuprofen group].Results: First request of analgesics, total opioid consumption and VAS showed no significant differences between two groups except after 4hours and 8 hours postoperatively which showed significant decrease in diclofenac group than ibuprofen group. Also patient satisfaction was higher in Diclofenac group. There was increase in bleeding tendency [APTT, BT, and HB results] and abnormal abdominal bleeding attacks in diclofenac group.Conclusion: Diclofenac decreases postoperative pain with higher potency than ibuprofen but unfortunately with more tendency to gastrointestinal complications and bleeding tendency. |
| Databáze: | Directory of Open Access Journals |
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