Mineralized Collagen: Rationale, Current Status, and Clinical Applications
| Autor: | Zhi-Ye Qiu, Yun Cui, Chun-Sheng Tao, Zi-Qiang Zhang, Pei-Fu Tang, Ke-Ya Mao, Xiu-Mei Wang, Fu-Zhai Cui |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
mineralized collagen
collagen hydroxyapatite biomineralization self-assembly medical device product clinical application Technology Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85 |
| Zdroj: | Materials, Vol 8, Iss 8, Pp 4733-4750 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1996-1944 |
| DOI: | 10.3390/ma8084733 |
| Popis: | This paper presents a review of the rationale for the in vitro mineralization process, preparation methods, and clinical applications of mineralized collagen. The rationale for natural mineralized collagen and the related mineralization process has been investigated for decades. Based on the understanding of natural mineralized collagen and its formation process, many attempts have been made to prepare biomimetic materials that resemble natural mineralized collagen in both composition and structure. To date, a number of bone substitute materials have been developed based on the principles of mineralized collagen, and some of them have been commercialized and approved by regulatory agencies. The clinical outcomes of mineralized collagen are of significance to advance the evaluation and improvement of related medical device products. Some representative clinical cases have been reported, and there are more clinical applications and long-term follow-ups that currently being performed by many research groups. |
| Databáze: | Directory of Open Access Journals |
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