Analysis of the Distribution of Total Phosphine and the Characteristics of Phosphine Poisoning in 29 Victims

Autor: YAN Hui, DU Meng, QIAO Zheng, XIANG Ping, SHEN Bao-hua, SHEN Min, LIU Wei
Jazyk: čínština
Rok vydání: 2022
Předmět:
Zdroj: Fayixue Zazhi, Vol 38, Iss 2, Pp 254-257 (2022)
Druh dokumentu: article
ISSN: 1004-5619
DOI: 10.12116/j.issn.1004-5619.2020.300901
Popis: ObjectiveTo study the distribution of total phosphine in phosphine poisoning victims and summarize the characteristics of phosphine poisoning cases.MethodsThe phosphine and its metabolites in the biological samples of 29 victims in 16 phosphine poisoning cases were qualified and quantified by headspace gas chromatography-mass spectrometry.ResultsFive victims among 29 were poisoned by ingestion of aluminium phosphide and 24 by inhalation of phosphine gas. Phosphine metabolites were detected in the biological samples of 23 victims, and the concentrations of total phosphine in blood ranged 0.5-34.0 μg/mL. The total concentration of phosphine in liver tissue was up to 71.0 μg/g. Phosphine was not detected in the blood of the other six survived victims, which may be related to the small amount of phosphine exposure and the delay in blood sampling.ConclusionThe total concentration of phosphine in blood and tissues caused by aluminum phosphine ingestion is higher than that caused by phosphine gas inhalation. The death cases of phosphine inhalation are characterized by long exposure time, repeated exposures and age susceptibility.
Databáze: Directory of Open Access Journals