Possible Role for Interleukin-5 in Asthma
| Autor: | Yacoob Y. Al-Rubaeyi, Batool A. Al-Haidary, Wala'a E. Jasim |
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| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: | |
| Zdroj: | مجلة كلية الطب, Vol 48, Iss 4 (2007) |
| Druh dokumentu: | article |
| ISSN: | 0041-9419 2410-8057 16852265 |
| Popis: | Background: Asthma is an allergic disease characterized by airway obstruction as a result of cellular accumulation due to the liberation of certain mediators. Among those mediators are the cytokines such as IL-5. Patients & Methods: Interleukin-5 concentration has been estimated in 94 sera samples of Asthmatic patients in comparison with 41 non-asthmatic bronchitis as patient controls in addition to 30 apparent healthy control group using ELISA method. Results & Conclusions: There is highly significant elevation of IL-5 in the asthmatic cases in comparison with healthy controls (P< 0.001). We conclude that this cytokine may play the major role in asthmatic attack & it may be a good marker for the disease. |
| Databáze: | Directory of Open Access Journals |
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