Three New Asperentin Derivatives from the Algicolous Fungus Aspergillus sp. F00785

Autor: Qian Tang, Kai Guo, Xiao-Yang Li, Xiu-Ying Zheng, Xiang-Jian Kong, Zhong-Hui Zheng, Qing-Yan Xu, Xianming Deng
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Marine Drugs, Vol 12, Iss 12, Pp 5993-6002 (2014)
Druh dokumentu: article
ISSN: 1660-3397
DOI: 10.3390/md12125993
Popis: Three new asperentin-type compounds, 6-O-α-d-ribosylasperentin (1) and 6-O-α-d-ribosyl-8-O-methylasperentin (2) and 5-hydroxyl-6-O-methylasperentin (3), along with asperentin (4) and its known analogues (5–9), were isolated from a halotolerant Aspergillus sp. strain F00785, an endotrophic fungus from marine alga. Their structures were determined using extensive NMR and HRESIMS spectroscopic analysis, including the X-ray crystallographic data for the assignment of the absolute configurations of compound 9. Compound 4 exhibited highly potent inhibitory activity against crop pathogens, Colletotrichum gleosporioides Penz. and Colletotrichum gleosporioides (Penz.) Sacc.
Databáze: Directory of Open Access Journals