Research progress on the pathogenesis of rapid eye movement sleep behavior disorder and neurodegenerative diseases

Autor: Hai-yang JIANG, Jin-sha HUANG, Tao WANG
Jazyk: English<br />Chinese
Rok vydání: 2017
Předmět:
Zdroj: Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 17, Iss 10, Pp 717-722 (2017)
Druh dokumentu: article
ISSN: 1672-6731
Popis: Rapid eye movement sleep behavior disorder (RBD) is a sleep disorder characterized by the disappearance of muscle relaxation and enacting one's dreams during rapid eye movement (REM), with most of the dreams being violent or aggressive. Prevalence of RBD, based on population, is 0.38%-2.01%, but it becomes much higher in patients with neurodegenerative diseases, especially α - synucleinopathies. RBD may herald the emergence of α-synucleinopathies by decades, thus it may be used as an effective early marker of neurodegenerative diseases. In this review, we summarized the progress on the pathogenesis of RBD and its relationship with neurodegenerative diseases. DOI: 10.3969/j.issn.1672-6731.2017.10.003
Databáze: Directory of Open Access Journals