Enhancing fracture risk indication: The impact of bone load index and muscle fat infiltration on vertebral compression fracture

Autor: Xiao-Yue Jiang, Zhi-Yang Tang, Bo-Wen Liu, Si-Yuan Lu, Dong-Gang Pan, Hui Jiang, Xiu-Hong Shan
Jazyk: angličtina
Rok vydání: 2025
Předmět:
Zdroj: Experimental Gerontology, Vol 199, Iss , Pp 112654- (2025)
Druh dokumentu: article
ISSN: 1873-6815
DOI: 10.1016/j.exger.2024.112654
Popis: Purpose: This study aims to identify risk factors for vertebral compression fracture and enhance the ability to indicate fracture risk. Methods: A retrospective collection of clinical and imaging data was conducted for patients with vertebral compression fractures and control subjects who underwent quantitative computed tomography scans. Stepwise logistic regression analysis was employed to identify variables associated with fractures, constructing both unadjusted model and adjusted model. Results: Compared with the non-fracture group, the fracture group showed significant differences in weight, body mass index (BMI), bone mineral density (BMD), vertebral cross-sectional area, paraspinal muscle area and right psoas major muscle fat area (all P
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