Hybrid tumor of central giant cell granuloma and trabecular juvenile ossifying fibroma of the mandible: A rare event in the oral cavity with a review on pathogenesis

Autor: Kundendu Arya Bishen, Rajesh Kumar Prajapati, Himanshu Singh, Shweta Rehani
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Indian Journal of Pathology and Microbiology, Vol 67, Iss 3 (2024)
Druh dokumentu: article
ISSN: 0377-4929
0974-5130
DOI: 10.4103/ijpm.ijpm_623_22
Popis: Hybrid tumors are rare lesions having features of multiple diseases in one lesion. A hybrid tumor of central giant cell granuloma (CGCG) and central ossifying fibroma (COF) shows the presence of microscopically large areas with CGCG character and large areas with COF features inside a single clinical lesion, separated by a transition zone. A rare type of COF is juvenile ossifying fibroma (JOF)-trabecular variant in the mandible. We present a unique and rare case of a hybrid tumor of the CGCG-JOF-trabecular variant in the mandible of a 14-year-old female which initially diagnosed with CGCG. The ambiguous pathogenesis of hybrid tumors and giant cells is reviewed. The goal of this article is to highlight the importance of careful clinical, radiological, and histopathological examination of each case to prevent misdiagnoses and recurrences. Similar and other cases must be reported in order to better understand the interrelationship between these hybrid lesions and their biological behavior.
Databáze: Directory of Open Access Journals
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