Pectus Excavatum and Risk of Right Ventricular Failure in Left Ventricular Assist Device Patients

Autor: Casper F. Zijderhand, Yunus C. Yalcin, Jelena Sjatskig, Daniel Bos, Alina A. Constantinescu, Olivier C. Manintveld, Ozcan Birim, Jos A. Bekkers, Ad J. J. C. Bogers, Kadir Caliskan
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Reviews in Cardiovascular Medicine, Vol 24, Iss 11, p 313 (2023)
Druh dokumentu: article
ISSN: 1530-6550
DOI: 10.31083/j.rcm2411313
Popis: Background: Right ventricular failure (RVF) is a significant cause of morbidity and mortality in patients with a left ventricular assist device (LVAD). This study is aimed to investigate the influence of a pectus excavatum on early and late outcomes, specifically RVF, following LVAD implantation. Methods: A retrospective study was performed, that included patients with a HeartMate 3 LVAD at our tertiary referral center. The Haller index (HI) was calculated using computed tomography (CT) scan to evaluate the chest-wall dimensions. Results: In total, 80 patients (median age 57 years) were included. Two cohorts were identified: 28 patients (35%) with a normal chest wall (HI 30 days) recurrent readmission for RVF occurred more often in patients with pectus excavatum (p = 0.008). The onset of late RVF started around 18 months after implantation and increased thereafter in the overall study cohort. Conclusions: Pectus excavatum is observed frequently in patients with a LVAD implantation. These patients have an increased rate of readmissions and late RVF. Further investigation is required to explore the extent and severity of chest-wall abnormalities on the risk of RVF.
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