Testicular swelling leading to a diagnosis of adrenocortical carcinoma – co-incidence or causation?

Autor: Maria Batool, David Fennell, David Slattery, Eamon Leen, Liam Cormican, Seamus Sreenan, John H McDermott
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-4 (2021)
Druh dokumentu: article
ISSN: 2052-0573
DOI: 10.1530/EDM-20-0177
Popis: Adrenocortical carcinoma (ACC) is a rare malignancy with an incidence of 0.7–2.0 cases/million/year. A majority of patients present with steroid hormone excess or abdominal mass effects, and in 15% of patients ACC is discovered incidentally. We present a case of 30-year-old otherwise asymptomatic Caucasian male who presented with a testicular swelling. Subsequent imaging and investigations revealed disseminated sarcoidosis and an 11 cm adrenal lesion. An adrenalectomy was performed. Histological examination of the resected specimen confirmed an ACC and also demonstrated a thin rim of adrenal tissue containing non-caseating granulomas, consistent with adrenal sarcoid.
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