The Role of Hemogram Parameters in Predicting the Severity of Pulmonary Embolism
| Autor: | Kaan Kara, Sinem Nedime Sökücü, Seda Tural Önür, Cengiz Özdemir, Fatma Tokgöz Akyil, Özlem Kahya |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | İstanbul Medical Journal, Vol 23, Iss 3, Pp 199-204 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2619-9793 2148-094X |
| DOI: | 10.4274/imj.galenos.2022.03367 |
| Popis: | Introduction:Acute pulmonary embolism (PE) is a disease with serious mortality and morbidity. Therefore, early diagnosis and treatment are important. A PE is a process accompanied by inflammation. Therefore, our study was designed to examine the relationship between hemogram parameters, which are easily accessible and indicative of inflammation, and late mortality from PE.Methods:Two hundred and two patients who were hospitalized in our hospital between January 1, 2017 and July 1, 2020 and who were diagnosed with pulmonary angio computed tomography were included. Demographic and clinical data, laboratory, radiology and echocardiography results of the patients were analyzed retrospectively from the hospital information system.Results:Seventy-eight of 202 patients included in the study were male (38.6%), 124 females (61.4%), mean age was 58.27±16.26 years. According to the results of univariate Cox regression analysis, age [hazard ratio (HR): 1,058, p=0.001], D-dimer (HR: 1,057, p=0.015), presence of malignancy (HR: 6,274, p=0.001), trauma history ( HR: 2,931, p=0.039), long travel history (HR: 0.163, p=0.003), C-reactive protein (HR: 1,004, p=0.021), PE severity index (HR: 1,033, p=0.001), EF (HR: 0.944 , p=0.001), red-cell distribution width (HR: 1,125, p=0.001), lymphocyte (HR: 0.999, p=0.001), platelet-lymphocyte ratio (PLR) (HR: 1.013, p=0.001) and neutrophil-lymphocyte ratio (NLR) (HR: 1,017, p=0.001) significantly and it was associated with mortality.Conclusion:Because of our study, we determined that NLR and PLR can be used as 12-month prognostic factors in patients with acute PE. |
| Databáze: | Directory of Open Access Journals |
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