Body Composition in Young Adults Living With a Fontan Circulation: The Myopenic Profile

Autor: Derek Tran, Paolo D'Ambrosio, Charlotte E. Verrall, Chantal Attard, Julie Briody, Mario D'Souza, Maria Fiatarone Singh, Julian Ayer, Yves d'Udekem, Stephen Twigg, Glen M. Davis, David S. Celermajer, Rachael Cordina
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 8 (2020)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.119.015639
Popis: Background We sought to characterize body composition abnormalities in young patients living with a Fontan circulation and explore potential pathophysiologic associations. Methods and Results Twenty‐eight patients with a Fontan circulation were prospectively recruited in this cross‐sectional study. Participants underwent cardiopulmonary exercise testing, dual‐energy X‐ray absorptiometry, echocardiography, and biochemical assessment. Mean age was 26±7 years. Skeletal muscle mass, estimated by appendicular lean mass index Z score, was reduced compared with reference data (−1.49±1.10, P
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