Synthesis, Antioxidant, Antimicrobial, Antimycobacterial, and Cytotoxic Activities of Azetidinone and Thiazolidinone Moieties Linked to Indole Nucleus

Autor:	A. R. Saundane, Prabhaker Walmik
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Chemistry QD1-999
Zdroj:	Journal of Chemistry, Vol 2013 (2013)
Druh dokumentu:	article
ISSN:	2090-9063 2090-9071
DOI:	10.1155/2013/543815
Popis:	2-N-(2-Phenyl-1H-indol-3-yl)imino-4-arylthiazoles (3a–c) were used as key synthons for the preparation of (4-arylthiazol-2-yl)-4-(2-phenyl-1H-indol-3-yl)azetidin-2-ones (4a–c) and 3-(4-arylthiazol-2-yl)-2-(2-phenyl-1H-indol-3-yl)thiazolidin-4-ones (5a–c). These newly synthesized compounds have been characterized with the help of IR, 1H NMR, 13C NMR, and mass spectral studies. All compounds were screened for their antioxidant, antimicrobial, antimycobacterial, and cytotoxic activities. Some of the compounds displayed excellent activity.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/c1b6e760d9e249348c82ccaba2d7dac9 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF