NONINVASIVE EVALUATION OF VASCULAR WALL STIFFNESSIN HEALTHY ADOLESCENTS, THE RISK FACTORS FOR ARTERIAL HYPERTENSION

Autor: G. P. Filippov, K. V. Boronenko, I. V. Plotnikova, Ye. S. Sitkova
Jazyk: English<br />Russian
Rok vydání: 2015
Předmět:
Zdroj: Бюллетень сибирской медицины, Vol 14, Iss 4, Pp 82-86 (2015)
Druh dokumentu: article
ISSN: 1682-0363
1819-3684
DOI: 10.20538/1682-0363-2015-4-82-86
Popis: Objective. To evaluate the main indicators characterizing the rigidity of the vascular wall in healthy ado-lescents with such risk factors (RF) for arterial hypertension (AH) as a family history on hypertension and smoking. Identify changes in the initial elastic-elastic properties of the arteries at the preclinical stage of development of hypertension.Material and methods. It was formed two groups of comparison. Age studied from 13 to 17 years (mean age (15.00 ± 0.31) years). The first group consisted of 30 healthy adolescents whose parents suffer from hypertension from a young age. The second group consisted of 30 healthy smokers teenager from healthy parents. The control group consisted of 30 healthy adolescents from healthy parents. Determines the basic stiffness of the vascular wall: PWV, CAVI, SAI.Results. A significant in crease in the indicators characterizing the rigidity of the vascular wall in the two comparison groups relative to the control. PWV: 6,89 ± 0,56 (first group), 7.13 ± 0.55 (second group) and 5.5 ± 0.41 (control), p < 0.05.L-CAVI: 5,46 ± 0,39 (first group), 5.84 ± 0.61 (second group) and 4.32 ± 0.41 (control), p < 0.05.R-CAVI: 5,63 ± 0,39 (first group), 5.89 ± 0.56 (second group) and 4.49 ± 0.41(control), p < 0.05. R-AI: 0,89 ± 0,09 (first group), 0.95 ± 0.12 (second group) and 0.62 ± 0.1 (control), p < 0.05.Smoking teenagers and adolescents with family history of hypertension, there are changes in the initial stiffness of the vessel wall, which requires the allocation of at-riskfor the development of hypertension and prevention activities at the preclinical stage of development ofthe disease.
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