Oral Lichenoid Reaction: An Uncommon Side Effect of Rituximab

Autor: Amerigo Giudice, Francesco Liborio, Fiorella Averta, Selene Barone, Leonzio Fortunato
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Case Reports in Dentistry, Vol 2019 (2019)
Druh dokumentu: article
ISSN: 2090-6447
2090-6455
DOI: 10.1155/2019/3154856
Popis: Oral lichenoid reactions (OLR) can be caused by systemic drug exposure. To the best of our knowledge, this is the second report describing a case of OLR induced by rituximab administration in a patient with a diagnosis of non-Hodgkin B-cell lymphoma. After 5 doses of rituximab, a typical pattern of OLP was identified with bilateral and symmetrical lesions on the buccal mucosa and on the right lingual margin. This temporal relationship suggested a probable association between oral lesions and drug therapy. The clinical diagnosis of a rituximab-induced OLR was confirmed by an incisional biopsy reporting a histopathological result of lichenoid mucositis consistent with oral lichen planus. Because of the increasing use of rituximab, it is necessary to know and recognize this uncommon side effect.
Databáze: Directory of Open Access Journals
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