Short pulsed microwave ablation: computer modeling and ex vivo experiments
| Autor: | Aleksandar Radosevic, Diego Prieto, Fernando Burdío, Enrique Berjano, Punit Prakash, Macarena Trujillo |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | International Journal of Hyperthermia, Vol 38, Iss 1, Pp 409-420 (2021) |
| Druh dokumentu: | article |
| ISSN: | 0265-6736 1464-5157 02656736 |
| DOI: | 10.1080/02656736.2021.1894358 |
| Popis: | Purpose To study the differences between continuous and short-pulse mode microwave ablation (MWA). Methods We built a computational model for MWA including a 200 mm long and 14 G antenna from Amica-Gen and solved an electromagnetic-thermal coupled problem using COMSOL Multiphysics. We compared the coagulation zone (CZ) sizes created with pulsed and continuous modes under ex vivo and in vivo conditions. The model was used to compare long vs. short pulses, and 1000 W high-powered short pulses. Ex vivo experiments were conducted to validate the model. Results The computational models predicted the axial diameter of the CZ with an error of 2–3% and overestimated the transverse diameter by 9–11%. For short pulses, the ex vivo computer modeling results showed a trend toward larger CZ when duty cycles decreases. In general, short pulsed mode yielded higher CZ diameters and volumes than continuous mode, but the differences were not significant ( |
| Databáze: | Directory of Open Access Journals |
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