Epidemiology of gonorrhea in countries of the Middle East and North Africa: systematic review, meta analyses, and meta regressions

Autor: Hiam Chemaitelly, Manale Harfouche, Alex Smolak, Rwedah Ageeb, Yousra A. Mohamoud, Ahmed S. Alaama, Joumana G. Hermez, Laith J. Abu-Raddad
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Global and Public Health, Vol 2, Iss 1, Pp 1-20 (2024)
Druh dokumentu: article
ISSN: 2731-913X
DOI: 10.1186/s44263-024-00088-9
Popis: Abstract Background The epidemiology of Neisseria gonorrhoeae (NG) infection in the Middle East and North Africa (MENA) region remains poorly understood, despite the global recognition of its disease burden and the growing concern regarding antimicrobial resistance. This study aimed to systematically review the evidence on NG prevalence in MENA, estimate the pooled mean prevalence across different populations, and explore population-level associations with prevalence as well as sources of between-study heterogeneity. Methods The study conducted a systematic review, risk of bias assessment, meta-analyses, and meta-regressions, utilizing both published and unpublished evidence sourced from international, regional, and national databases, in adherence to PRISMA guidelines. Random-effects meta-analyses and meta-regressions were employed to analyze the data. Results The study identified 341 NG prevalence measures from 21 countries in MENA. The pooled mean prevalence of current urogenital infection was 1.9% (95% confidence interval (CI) 1.1–2.8%) in the general population, with a higher pooled prevalence in studies with sample sizes
Databáze: Directory of Open Access Journals
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