Early or delayed cord clamping during transition of term newborns: does it make any difference in cerebral tissue oxygenation?

Autor: Baran Cengiz Arcagok, Hulya Bilgen, Hulya Ozdemir, Asli Memisoglu, Dilsad Save, Eren Ozek
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Italian Journal of Pediatrics, Vol 50, Iss 1, Pp 1-9 (2024)
Druh dokumentu: article
ISSN: 1824-7288
DOI: 10.1186/s13052-024-01707-9
Popis: Abstract Background According to the World Health Organization’s recommendation, delayed cord clamping in term newborns can have various benefits. Cochrane metaanalyses reported no differences for mortality and early neonatal morbidity although a limited number of studies investigated long-term neurodevelopmental outcomes. The aim of our study is to compare the postnatal cerebral tissue oxygenation values in babies with early versus delayed cord clamping born after elective cesarean section. Methods In this study, a total of 80 term newborns delivered by elective cesarean section were included. Infants were randomly grouped as early (clamped within 15 s, n:40) and delayed cord clamping (at the 60th second, n:40) groups. Peripheral arterial oxygen saturation (SpO2) and heart rate were measured by pulse oximetry while regional oxygen saturation of the brain (rSO2) was measured with near-infrared spectrometer. Fractional tissue oxygen extraction (FTOE) was calculated for every minute between the 3rd and 15th minute after birth. (FTOE = pulse oximetry value-rSO2/pulse oximetry value). The measurements were compared for both groups. Results The demographical characteristics, SpO2 levels (except postnatal 6th, 8th, and 14th minutes favoring DCC p 0.05). rSO2 values were significantly higher while FTOE values were significantly lower for every minute between the 3rd and 15th minutes after birth in the delayed cord clamping group (p
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