Sociodemographic and Clinical Predictors of Weight Gain During the First Year of Antiretroviral Therapy among Adults Living With HIV in Urban Tanzania
| Autor: | Pilly Chillo MD, PhD, Alfa Muhihi MD, MPH, Goodarz Danaei MD, ScD, Muhammad Bakari MSc, Gideon Kwesigabo MD, MSc, MEd, PhD, Marina Njelekela MD, PhD, MPH, Nzovu Ulenga PhD, Wafaie W. Fawzi MBBS, DrPH, Ferdinand Mugusi MD, MMed, Christopher R. Sudfeld ScD |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Journal of the International Association of Providers of AIDS Care, Vol 23 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2325-9582 23259582 |
| DOI: | 10.1177/23259582241281010 |
| Popis: | Antiretroviral therapy (ART) has improved the survival of people living with HIV (PLHIV) but this success has been accompanied by an increase in noncommunicable diseases. We conducted a prospective cohort study of 4000 adult PLHIV who were initiating ART in Dar es Salaam, Tanzania, to assess weight gain during the first year of treatment and associated sociodemographic and clinical factors. Anthropometric data were collected at ART initiation and monthly follow-up visits. The mean weight gain during the first year of treatment was 2.6 ± 0.3 kg, and the prevalence of overweight or obesity increased from 26.3% at baseline to 40.7%. Female sex, greater household wealth, lower CD4-T-cell counts, higher WHO HIV disease stage, and pulmonary tuberculosis were associated with a greater increase in body mass index ( P < .05). Weight gain following ART initiation was common but was greater among females and PLHIV with advanced HIV or comorbidities. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|