Benefits of Study Participation for Patients with Advanced Cancer Receiving Radiotherapy: A Prospective Observational Study
| Autor: | Asta Bye, Ellen Bjerkeset, Hanne Stensheim, Jon H. Loge, Marianne J. Hjermstad, Pal Klepstad, Ragnhild Habberstad, Stein Kaasa, Nina Aass |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Palliative Medicine Reports, Vol 3, Iss 1, Pp 264-271 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2689-2820 89538137 |
| DOI: | 10.1089/PMR.2022.0044 |
| Popis: | Background: Patients with advanced cancer and bone metastases may have unmet palliative care (PC) needs that go unnoticed during clinical oncological practice. This observational study describes interventions that were initiated as the patients participated in the Palliative Radiotherapy and Inflammation Study (PRAIS). It was hypothesized that the patients would benefit from study participation due to PC interventions initiated by the study team. Methods: A retrospective review of patients' electronic records. Patients with advanced cancer and painful bone metastases included in PRAIS were eligible. All patients met with the study team before start of radiotherapy, after completion of Patient Reported Outcome Measures. Interventions initiated by the study team were documented in the patients' electronic records. Results: A total of 133 patients were reviewed: 63% males, mean (standard deviation [SD]) age 65 (9.6) and mean (SD) Karnofsky performance status (KPS) score 73.2 (9.1). Interventions were initiated in 50% (n?=?67) of the patients. Changes in opioid management (69%), treatment of constipation (43%), and nausea (24%) and nutritional advice were most frequent (21%). Patients receiving interventions had lower mean KPS (70 vs. 77 p?0.001), shorter survival time after study inclusion (median 28 vs. 57.5 weeks p?=?0.005) and were more often opioid na?ve (12% vs. 39% p? |
| Databáze: | Directory of Open Access Journals |
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