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BackgroundIgG4-related disease (IgG4-RD) is a rare fibro-inflammatory disease, which is prone to missed diagnosis or misdiagnosis due to nonspecific clinical manifestations.ObjectiveTo analyze the clinical characteristics of IgG4-related disease (IgG4-RD) .MethodsA retrospective design was adopted. Participants were 106 IgG4-RD patients recruited from the First Affiliated Hospital of Zhengzhou University from January 2015 to September 2019. Their clinical data were collected, including demographics, results of serological examinations, imaging examinations, histopathological examinations and treatment status. Data of follow-up conducted by telephone or checking medical history data as of January 1, 2020 were also collected.ResultsOf the 106 cases, 69 were male and 37 were female, with a mean age of onset of (54.6±13.1) years. The most common organs involved were lymph nodes (67.0%) , salivary glands (37.7%) , and pancreas (35.8%) . Single organ involvementoccurred in 17 patients (16.0%) . The median number of involved organs was 3 (2, 4) . Women had higher incidence of salivary gland involvement, lacrimal gland involvement as well as lower incidence of pancreatic involvement than men did (P |
