Flow-Synchronized Nasal Intermittent Positive Pressure Ventilation for Infants

Autor: C. Gizzi, P. Papoff, I. Giordano, L. Massenzi, C. S. Barbàra, M. Campelli, V. Panetta, R. Agostino, C. Moretti
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Critical Care Research and Practice, Vol 2012 (2012)
Druh dokumentu: article
ISSN: 2090-1305
2090-1313
DOI: 10.1155/2012/301818
Popis: Aim. To evaluate whether synchronized-NIPPV (SNIPPV) used after the INSURE procedure can reduce mechanical ventilation (MV) need in preterm infants with RDS more effectively than NCPAP and to compare the clinical course and the incidence of short-term outcomes of infants managed with SNIPPV or NCPAP. Methods. Chart data of inborn infants 0.4, respiratory acidosis, or intractable apnoea that occurred within 72 hours of surfactant administration. Results. Eleven out of 31 (35.5%) infants in the NCPAP group and 2 out of 33 (6.1%) infants in the SNIPPV group failed the INSURE approach and underwent MV (). Fewer infants in the INSURE/SNIPPV group needed a second dose of surfactant, a high caffeine maintenance dose, and pharmacological treatment for PDA. Differences in O2 dependency at 28 days and 36 weeks of postmenstrual age were at the limit of significance in favor of SNIPPV treated infants. Conclusions. SNIPPV use after INSURE technique in our NICU reduced MV need and favorably affected short-term morbidities of our premature infants.
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