Data on atherosclerosis specific antibody conjugation to nanoemulsions

Autor: Geoffrey Prévot, Martine Duonor-Cérutti, Mélusine Larivière, Jeanny Laroche-Traineau, Marie Josée Jacobin-Valat, Philippe Barthélémy, Gisèle Clofent-Sanchez, Sylvie Crauste-Manciet
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Data in Brief, Vol 15, Iss , Pp 824-827 (2017)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2017.10.058
Popis: This article present data related to the publication entitled âIron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imagingâ (Prévot et al., 2017) [1]. Herein we describe the engineering in the baculovirus-insect cell system and purification processes of the human scFv-Fc TEG4-2C antibody, specific of platelets within the atheroma plaque. For molecular targeting purpose, atheroma specific antibody was conjugated to nanoemulsions (NEs) using a heterobifunctional linker (DSPE-PEG-maleimide). Atheroma labelling was assayed by immunochemistry on arterial sections from rabbits.
Databáze: Directory of Open Access Journals