COMPARATIVE EVALUATION OF PORCINE AND BUFFALO SMALL INTESTINAL SUBMUCOSA FOR THE DEVELOPMENT OF EXTRACELLUALR MATRIX SCAFFOLDS

Autor: V. N. Vasudevan, P. Kuttinarayanan
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of Veterinary and Animal Sciences, Vol 47, Iss 2, Pp 54-56 (2016)
Druh dokumentu: article
ISSN: 0971-0701
2582-0605
Popis: Small intestinal submucosa (SIS) fromc6-8 months old Large White Yorkshire (LWY)cpigs and 18-24 months old buffaloes werecevaluated for the development of extracellularcmatrix scaffolds. The thickness of SIS from buffalo and LWY pigs did not differ significantly.cBuffalo SIS had significantly higherfat and totalccollagen contents, and was more resistantcto collagenase degradation than that fromcLWY pigs, but showed a higher content of acid soluble collagen. Buffalo SIS could be a better raw material for scaffold preparation as it is a widely available low-cost by-product. However, the properties of the scaffold may alter with subsequent treatments like defatting, decellularization, cross linking and sterilization
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