Management of Psoriasis Herpeticum in Pregnancy: A Clinical Conundrum

Autor: Leanne Almario, Albert S. Antonyan, Dennis A. Porto, Hunter Gomez-Roberts, Ali Alhousseini, Bernard Gonik
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Case Reports in Obstetrics and Gynecology, Vol 2016 (2016)
Druh dokumentu: article
ISSN: 2090-6684
2090-6692
DOI: 10.1155/2016/5319425
Popis: Introduction. Kaposi varicelliform eruption (KVE) is a widespread cutaneous viral infection, most commonly herpes simplex virus, which affects patients with underlying dermatosis. When KVE occurs in a patient with a history of psoriasis, it is referred to as psoriasis herpeticum, a rare subtype of KVE with only a handful of cases reported in the literature. To the authors’ knowledge, we report for the first time a case of psoriasis herpeticum in pregnancy. Case Presentation. A 23-year-old woman in her third pregnancy presented at 26-week gestation with a 10-year history of psoriasis. Cutaneous examination revealed diffuse psoriatic plaques with scattered ~1 cm erosions. Punch biopsy of the skin revealed herpes simplex virus (HSV) infection within a psoriatic plaque, necessitating dermatological treatment. The patient experienced premature rupture of membranes at 37-week gestation. Pelvic exam showed no evidence of herpetic lesions. After labor augmentation, the patient delivered a healthy female infant with no evidence of HSV infection. Discussion. Psoriasis herpeticum is a rare and potentially devastating complication of an underlying dermatosis. With a paucity of data available to guide pregnancy-specific issues, the general management of this condition is controversial and requires a multidisciplinary care approach. Concerns for systemic infection in the mother and vertical transmission to the neonate are of critical importance.
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