| Autor: |
Jeong Bae Park, Kee Sik Kim, Ho Joong Youn, Sang Hong Baek, Kyu Hyung Ryu, Shung Chull Chae, Jang Ho Bae, Chang Gyu Park, Moo Yong Rhee, Soo Yeun Choi, Dong Ju Choi, Sung Ha Park, Se Joong Rim, Dong Gu Shin, Gae Hoon Kim, Jong Chun Park, Won Ho Kim, Wang Seong Ryu, Kyung Ho Youn, Jin Won Jeong, Young Moo Ro, Young Dae Kim, Dong Soo Kim, Myeng Chan Cho, Byung Hee Oh, Nam Sik Chung |
| Jazyk: |
angličtina |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Artery Research, Vol 3, Iss 3 (2009) |
| Druh dokumentu: |
article |
| ISSN: |
1876-4401 |
| DOI: |
10.1016/j.artres.2009.06.032 |
| Popis: |
Background: Aging exerts a number of deleterious changes in the cardiovascular system, and, in particular, on the large arteries. Previous studies have suggested that augmentation index (Aix) and aortic pulse wave velocity (aPWV) increase linearly with age, yet epidemiological data concerning arterial stiffness suggest that large artery stiffening predominantly occurs later in life. Therefore, the aim of the study was to test the hypothesis; 1) age-related changes in AIx are more prominent in younger individuals, whereas changes in aortic stiffness per se are more marked in older individuals, 2) whether these changes are similar between Caucasians and Koreans. Methods: 1,188 subjects aged 17 to 87 years (mean age of 45.5 years and female 52%) were included and all were apparently healthy and free of any medication for hypertension, diabetes and dyslipidemia. Aix and aPWV were measured by pp-1000 and Gaon 21 (both Hanbyul Medtech, Korea). Results: Women showed significantly higher central Aix (15.4 vs. 22.5 of men, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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