Malignant Solitary Fibrous Tumor of the Right Cerebellum: A Case Report

Autor: Ye-Tao Zhu, Yang Liu, Li-Gang Chen, Da-Ping Song
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Case Reports in Neurology, Vol 13, Iss 1, Pp 259-266 (2021)
Druh dokumentu: article
ISSN: 1662-680X
DOI: 10.1159/000510844
Popis: Solitary fibrous tumor is a very rare mesenchymal tumor that occurs mostly in the pleura, and there are few reported cases of a presence in the central nervous system, particularly in the cerebellum. In 2016, the WHO classified solitary fibrous tumors into grade I. In this article, we present a case of malignant solitary fibrous tumor recurring 8 years after surgery in a 63-year-old male. Magnetic resonance imaging showed low to intermediate mixed signal intensity on T1W1. Immunohistochemical staining positivity for Vimentin, CD99, CD34 and Bcl-2, it is consistent with the immunohistochemical characteristics of solitary fibrous tumor. We resected the patient’s tumor, and the patient was followed up for 3 months with no signs of recurrence. Solitary fibrous tumors are very rare in the central nervous system. Immunohistochemical staining positivity for CD34 and Bcl-2 is strongly expressed in most solitary fibrous tumor. Surgical resection is the preferred treatment. Due to the small number of cases, the biological behavior and prognosis of this tumor need to be further explored.
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