| Autor: |
Bachurska Svitlana Y., Staykov Dmitriy G., Ivanov Georgi P., Belovezhdov Veselin T. |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Folia Medica, Vol 58, Iss 1, Pp 48-53 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
1314-2143 |
| DOI: |
10.1515/folmed-2016-0007 |
| Popis: |
Introduction: Prostate carcinoma (PC) is the second most diagnosed cancer in men worldwide. Prostate tissue in needle biopsy expresses a wide variety of architectural patterns some of which are difficult to interpret. Immunohistochemical markers, such as AMACR, p63 and 34βE12 that are currently used in diagnosing prostate cancer, are of great value, but often their interpretation is ambiguous. In 2005 Tomlins et al. identified an emerging marker, erythroblastosis E26 rearrangement gene (ERG), which is a member of the family of genes encoding erythroblast-transformation specific transcription factors (ETS) with frequent expression in PC. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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