| Autor: |
G. de Jong, M.A. Gillissen, H. Spits, M.D. Hazenberg |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Immuno-Oncology and Technology, Vol 7, Iss , Pp 15-22 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2590-0188 |
| DOI: |
10.1016/j.iotech.2020.07.002 |
| Popis: |
For many high-risk haematologic malignancies, such as acute myeloid leukaemia, the success of therapy relies mainly on invoking a curative antitumour immune response. This can be achieved by inducing a graft-versus-leukaemia response following allogeneic haematopoietic cell transplantation. While the contribution of T cells and natural killer cells to graft-versus-leukaemia responses is established, the contribution of B cells and antibodies is relatively unexplored. This article reviews what is known about the contribution of B cells and tumour-specific antibody responses to a successful graft-versus-leukaemia response leading to eradication of the tumour. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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