A Comparative Study of Hypolipidemic Activities of the Extracts of Melissa officinalis and Berberis vulgaris in Rats
| Autor: | S Changizi Ashtiyani, A Zarei, S Taheri, A Rezaei, M Golshan, R Ghafarzadegan |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Journal of Medicinal Plants, Vol 12, Iss 47, Pp 38-47 (2013) |
| Druh dokumentu: | article |
| ISSN: | 2717-204X 2717-2058 |
| Popis: | Background: Hyperlipidemia is a heterogeneous group of disorders characterized by an excess of lipids in the bloodstream Objective: Given previous studies on barberry and Melissa officinalis extracts, this study aims at comparing hypolipidemic activities of Melissa officinalis extract and Berberis vulgaris. Methods: For the purpose of this study, 64 Wistar rats were selected and divided into 8 groups (n=8). The control group was administered with ordinary diet the sham group was administered with high-fat diet and intraperitoneally 0.2 ml/dl of the extract solvent (normal saline) and similarly, experimental groups received minimal, moderate and maximum dosages of barberry and Melissa officinalis extracts. The treatment groupchr('39')s was given high-fat diet for 21 days. After this period, blood samples were taken and the gathered data were analyzed using SPSS software. Results: The amount of cholesterol, triglyceride and LDL were increased in the model group compared to the control group, whereas the same substances were decreased significantly in the group receiving the extract compared to the model group (p |
| Databáze: | Directory of Open Access Journals |
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